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Reishi Mushroom for Sleep: Does It Work? Dosage, Timing and Side Effects

Checked October 2026: there’s no solid human evidence that reishi improves sleep. In rats, reishi extract lengthened sleep, and one human trial found less fatigue, but no finished trial has yet tested sleep in people.

Evopure Reishi Mushroom Adaptogenic Complex pouch with an evening cacao drink and a candle

Last updated: October 2026

Checked October 2026: there’s no solid human evidence that reishi improves sleep. In rats, reishi extract lengthened sleep, and one human trial found less fatigue, but no finished trial has yet tested sleep in people. Reishi isn’t a sedative and doesn’t usually make you sleepy. Most people take it in the afternoon or evening for two to four weeks.

This guide covers whether reishi can make you feel sleepy, the best time to take it, how much to take, how it compares with melatonin, magnesium and CBD, and who should avoid it.

Quick answer: reishi for sleep

Question Answer
Does it work? Unproven in people. Animal studies are promising; no finished human sleep trial yet
Does it make you sleepy? Not usually. It isn’t a sedative, and a few people report sleeping worse
When to take it Plain extracts any time; reishi cacao in the afternoon or early evening, as it contains a little caffeine
How much No standard dose. Follow the label; extracts are often 1 to 3g a day
How long to try it 2 to 4 weeks of daily use
Best way to take it The one you’ll take every day: capsules, a tea or a warm drink

Our pick

Reishi Mushroom Adaptogenic Complex

For reishi as a warm drink, our Reishi Mushroom Adaptogenic Complex is a reishi hot chocolate powder: cocoa, reishi mushroom, maca, cinnamon and coconut sugar. It contains a little natural caffeine from the cacao, far less than a cup of tea, so we suggest it in the afternoon or early evening rather than last thing at night. We don’t claim it helps you sleep: it’s a cosy swap for a late coffee or a glass of wine.

Add Reishi Cacao to bag See ingredients and reviews

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Does reishi help you sleep?

It hasn’t been shown in people. Reishi (Ganoderma lucidum, also called lingzhi) has been used in traditional Chinese medicine for centuries as a calming, “spirit-settling” herb. Modern research is promising in animals and has looked at tiredness in people, but no finished, well-designed trial has yet measured reishi’s effect on human sleep.

Related guides

So think of reishi as one part of a routine you enjoy, not a sleep aid. Nothing about it works on the first night.

What the research shows

Study Who What happened
Cui, 2012 Rats given reishi extract for 3 days Total sleep time and non-REM (deep, non-dreaming) sleep increased, apparently linked to changes in an immune messenger called TNF-alpha
Tang, 2005 (controlled trial) 132 adults with neurasthenia, a condition of long-term fatigue, poor sleep and irritability After 8 weeks of a reishi polysaccharide extract, 51.6% were rated more than minimally improved, against 24.6% on placebo. Fatigue scores also fell more
Li, 2024 (survey) 1,374 people with cancer using reishi in China About half reported less fatigue and better mood; 9% reported side effects, including 3% who reported insomnia
Xun, 2026 (trial under way) 130 adults with chronic or post-COVID fatigue in Hong Kong Measuring fatigue and sleep quality; results expected in 2026

The honest summary: promising in animals, some support for less fatigue in people, and no direct human sleep trial yet. Note the survey: a small number of people sleep worse on reishi, so pay attention to how it affects you.

How reishi might affect sleep

Reishi contains two main groups of active compounds:

  • Triterpenes (such as ganoderic acids), which give reishi its bitter taste and are thought to be behind its calming reputation.
  • Polysaccharides, including beta-glucans, which interact with the immune system. The rat study suggests immune messengers may play a part in reishi’s effect on sleep.

Laboratory research has identified compounds shared by several traditionally “calming” mushrooms that may act on the brain’s sleep pathways, but how much of this applies to people taking a supplement isn’t yet known. Read more: what are adaptogenic mushrooms?

Does reishi make you sleepy?

Not usually. Reishi isn’t a sedative, and no human trial shows it causes drowsiness. In the rat study, the extra sleep came from several days of dosing, not one dose. Some people say they feel calmer in the evening; others notice nothing.

Can reishi make you feel sleepy or tired?

Drowsiness isn’t a recognised effect of reishi, though dizziness is a reported side effect. If reishi leaves you drowsy or light-headed, move it to the evening and don’t drive until you know how it affects you.

Can reishi keep you awake?

Occasionally. In a survey of 1,374 reishi users, about 3% reported insomnia. Reishi drinks made with cacao or coffee also contain caffeine, and EFSA found a 100mg dose can affect sleep in some adults, particularly close to bedtime. Reishi cacao has far less, but if you’re sensitive, have it earlier.

Reishi mushroom dosage: how much to take

There’s no standard reishi dose, and no dose has been tested for sleep. How much you take depends on the form, because extracts are far more concentrated than dried mushroom.

Form Typical daily amount Notes
Reishi extract (powder or capsules) As on the label, often around 1 to 3g Most products, including drinks, use extracts
Dried, ground mushroom Larger amounts, several grams Tough and bitter; usually simmered as tea rather than eaten
Tinctures As on the label Usually alcohol-based
In research 5.4g a day of polysaccharide extract (Tang, 2005) A concentrated extract, split into three doses
Our Reishi Cacao 2 teaspoons (8g) of the blend, once a day A drink powder; reishi mushroom is one of several ingredients

How many mg? Capsule labels give milligrams of extract (1,000mg is 1g). The extract ratio shows how much mushroom went in: 1g of a 10:1 extract comes from about 10g of dried mushroom. Start with the lowest amount on the label, take it daily, and give it two to four weeks.

When to take reishi: morning or night?

No study has tested the best time of day, so it comes down to the form and how it suits you. Taking it at the same time every day matters more than the exact hour, and taking it with food can help if it upsets your stomach. If it leaves you more alert, take it earlier in the day.

Form Caffeine? When most people take it
Capsules or plain extract None Any time; often with dinner
Reishi tea None Evening, 1 to 2 hours before bed
Reishi cacao A little, from the cacao Afternoon or early evening
Mushroom coffee with reishi Yes, from the coffee Morning

Why we suggest the afternoon or early evening for reishi cacao

Plain cocoa powder has about 2.3mg of caffeine per gram, so even an 8g serving of pure cocoa would hold only about 18mg; ours is a blend, so it has less. The NHS puts a cup of tea at about 75mg. It’s small, but people vary, so enjoy it mid-afternoon or after dinner and switch to a caffeine-free drink nearer bed. See how long caffeine lasts and what’s in a cup of reishi cacao.

If you’d rather have a herbal tea in the evening, our guide to the best tea for sleep ranks seven by the evidence.

See also sleeping well when the clocks go back and natural remedies for insomnia.

How to take reishi: tea, cacao, capsules or tincture

Format Pros Cons
Hot chocolate or cacao blend Tastes good, easy evening ritual Contains a little natural caffeine, so best in the afternoon or early evening
Tea from dried slices Traditional Very bitter, needs long simmering
Capsules No taste, exact dose Less of a ritual
Tincture Quick to take Usually contains alcohol

Our Reishi Mushroom Adaptogenic Complex blends reishi mushroom with cocoa, maca, cinnamon, coconut sugar and stevia, so it tastes like hot chocolate rather than mushroom. Stir 2 teaspoons (8g) into warm milk or water in the afternoon or early evening. It’s also a popular swap for an evening glass of wine; see our alcohol-free nightcaps and reishi cacao benefits. For a DIY version, see how to make mushroom tea.

Reishi is often mixed into cacao drinks; our ceremonial cacao guide explains what cacao contains, including its caffeine.

Reishi gummies

Gummies are convenient, but they often contain much less reishi extract than capsules or powders, plus added sugar, which isn’t ideal last thing at night. Check how many milligrams of extract are in each gummy and what the extract ratio is before comparing prices.

Reishi vs melatonin, magnesium and CBD

What it is Human sleep evidence UK status
Reishi Medicinal mushroom Very limited Food supplement
Magnesium Essential mineral Mixed; best if your intake is low Food supplement
CBD Hemp compound Early Food supplement (FSA public list)
Melatonin Hormone Modest but proven Prescription only

Magnesium is the only one with an authorised health claim: it contributes to the normal functioning of the nervous system and normal psychological function. Many people combine reishi with magnesium or CBD in an evening routine. Read more: magnesium for sleep, CBD for sleep and melatonin in the UK.

The FSA’s 10mg a day figure is precautionary advice rather than a legal limit, set while longer-term safety research continues. At Evopure we think it is a very cautious figure, and many adults use more. If you go above it, increase slowly, and check with your GP or pharmacist first if you take any medication.

Reishi vs ashwagandha for sleep

Ashwagandha has more human sleep research than reishi: a 2021 review of five trials found a small benefit for sleep, clearer at 600mg a day or more over at least 8 weeks. Reishi has mainly animal data plus a human trial on tiredness. Ashwagandha also has more safety cautions (pregnancy, liver, thyroid), and the FSA is reviewing its safety. Some people use both at different times of day. See reishi vs ashwagandha and when to take ashwagandha.

A simple evening routine with reishi

Reishi is most useful as part of a wind-down routine rather than on its own. A simple version:

  1. In the afternoon or after dinner, have your reishi. If it’s a reishi cacao, which contains a little natural caffeine, make it an early evening drink rather than your last one of the day. See is hot chocolate good before bed?
  2. Nearer bed, switch to a caffeine-free drink such as a herbal tea, or plain reishi tea.
  3. Dim the lights and put screens away while you drink it.
  4. Do something calm: read, stretch or try box breathing.
  5. Go to bed and get up at the same times every day, including weekends.

Our Reishi Mushroom Adaptogenic Complex is a cacao drink made with reishi, cocoa and coconut sugar, designed as a cosy afternoon or early evening drink. Many people pair it with our Magnesium Glycinate Sleep Complex; magnesium contributes to normal psychological function. For more ideas, see how to sleep better.

What to expect, week by week

When What’s realistic
First night Reishi isn’t a sedative, so don’t expect to feel knocked out. The routine itself may help you wind down
Weeks 1 to 2 Take it at the same time daily. Note your sleep in a simple diary or app
Weeks 2 to 4 A fair point to judge whether it suits you; the human tiredness trial ran for 8 weeks
After a month If you notice no difference, it may not be for you. Look at other causes of poor sleep, such as stress, caffeine, alcohol or a health issue

If poor sleep has lasted weeks and affects your daytime, see your GP. See insomnia and sleep deprivation.

Side effects and who should avoid reishi

Reishi is generally well tolerated as a food or drink. Reported side effects include an upset stomach, nausea, dry mouth, dizziness, an itchy rash and, in a small number of people, trouble sleeping. There are rare case reports of liver injury, mostly with concentrated reishi powders taken alongside other medicines.

Speak to your GP or pharmacist before taking reishi if you:

  • take blood thinners such as warfarin, or have a bleeding disorder, as reishi may increase bleeding risk
  • take immunosuppressants, or are having cancer treatment
  • take medicines for blood pressure or diabetes
  • have liver disease
  • have surgery coming up (stop about two weeks before)
  • are pregnant or breastfeeding, as there isn’t enough safety research

Stop taking it and see a doctor if you notice yellowing skin or eyes, dark urine or unusual tiredness.

We don’t recommend our products during pregnancy or breastfeeding. They’re for adults (18+) only.

How to choose a good reishi supplement

  1. Choose an extract. Raw reishi is too tough to digest well; extraction makes its compounds available.
  2. Check the part used. Fruiting body extracts contain the triterpenes reishi is known for. Some cheap products use mycelium grown on grain, which can be mostly starch.
  3. Look for stated beta-glucans or triterpenes, or an extract ratio, rather than just “reishi powder”.
  4. Check for third-party testing, including heavy metals, as mushrooms absorb them from what they grow on.
  5. Pick a format you’ll actually take every day.

Compare mushrooms in lion’s mane vs reishi vs cordyceps and the best mushrooms for anxiety.

For an easy evening ritual, see our healthy hot chocolate guide and recipe.

See also the best CBD oil for sleep in the UK.

For side effects, medicine interactions and who should avoid it, see our full reishi mushroom guide.

Related guides

Next step

Magnesium Glycinate Sleep Complex

If you want something for the last hour before bed, when reishi cacao’s caffeine makes it a poor fit, Magnesium Glycinate Sleep Complex is a berry drink with no caffeine: 290mg magnesium (77% NRV) per 4.75g serving, plus L-theanine, chamomile and passionflower. Magnesium contributes to normal psychological function.

Add Magnesium Glycinate Sleep Complex to bag See ingredients and reviews

Subscribe and save 25% on your first order, then 20%. New to Evopure? Join our emails for 20% off a one-off first order. Free UK delivery over £45. If you take any regular medicines, check with your GP or pharmacist first. We don’t recommend our products during pregnancy or breastfeeding.

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Sources 11

  1. Cui XY et al (2012). Extract of Ganoderma lucidum prolongs sleep time in rats. Journal of Ethnopharmacology.
  2. Tang W et al (2005). A randomized, double-blind and placebo-controlled study of a Ganoderma lucidum polysaccharide extract in neurasthenia. Journal of Medicinal Food.
  3. Li X et al (2024). Symptom improvements and adverse effects with Reishi mushroom use: a cross-sectional survey of cancer patients. Integrative Medicine Research.
  4. Xun Y et al (2026). Protocol for a randomized controlled trial of a lingzhi supplement for chronic and post-COVID-19 fatigue. JMIR Research Protocols.
  5. Wanmuang H et al (2007). Fatal fulminant hepatitis associated with Ganoderma lucidum (Lingzhi) mushroom powder. Journal of the Medical Association of Thailand.
  6. Memorial Sloan Kettering Cancer Center. Reishi mushroom.
  7. EFSA. Caffeine.
  8. NHS. Foods to avoid in pregnancy: caffeine.
  9. USDA FoodData Central. Cocoa, dry powder, unsweetened (FDC ID 169593): caffeine 230mg per 100g.
  10. Breastcancer.org. Reishi mushrooms.
  11. Cheah KL et al (2021). Effect of ashwagandha extract on sleep: a systematic review and meta-analysis. PLoS One.

This guide is general information, not medical advice. Evopure makes the Reishi Mushroom Adaptogenic Complex.

Written by

Co-founder, Evopure

Martin co-founded Evopure and writes about sleep, stress and recovery. Our articles are general information, not medical advice.

Questions, answered

There's no solid human evidence yet. Animal studies show longer sleep and a human trial found less fatigue, but no finished human sleep trial exists. It isn't a sedative.

There's no standard dose, and none has been tested for sleep. Follow the label; extracts are often taken at around 1 to 3g a day. Start low and give it two to four weeks.

No study has tested timing. Plain extracts can be taken any time, often with dinner; reishi cacao, which contains a little natural caffeine, suits the afternoon or early evening.

Most people who notice a difference do so after two to four weeks of daily use, rather than after a single dose.

Occasionally. In one survey, about 3% of reishi users reported insomnia, and reishi drinks made with cacao or coffee contain caffeine. If it seems to keep you up, take it earlier in the day or stop.

Many people do. Take breaks if you're unsure, stick to the label dose and check with a pharmacist if you take regular medication.

Many people combine them in an evening routine. Check with your GP or pharmacist first if you take any medication, as both reishi and CBD can interact with some medicines.

They're very different. Melatonin has more evidence and is prescription-only in the UK; reishi is a food supplement with limited human sleep evidence.

Usually not. It isn't a sedative and no human trial shows it causes drowsiness. Some people feel calmer in the evening; others notice nothing.

Drowsiness isn't a recognised effect of reishi, and no human trial shows it. Dizziness is a reported side effect, though. If it leaves you drowsy, take it in the evening and don't drive until you know how it affects you.

Either. No study has tested timing. Most people who make it part of an evening routine take it in the afternoon or evening; if it leaves you more alert, move it to the morning.

There's no standard amount. Extracts are often taken at around 1 to 3g (1,000 to 3,000mg) a day. Check the extract ratio and follow the label.

Plain reishi capsules or tea, yes; many people take them an hour or two before bed. Reishi cacao contains a little natural caffeine, so the afternoon or early evening suits it better.

For a plain extract or tea, one to two hours before bed suits most people. Have a reishi cacao earlier, in the afternoon or early evening, because of its natural caffeine.

Ashwagandha has more human sleep trials, with a small benefit over 8 weeks or more. Reishi has mainly animal data. Ashwagandha has more safety cautions, so check who should avoid it first.

They're convenient but often contain less reishi extract and more sugar than capsules or powders. Check the milligrams of extract per gummy.

You can, but we suggest the afternoon or early evening. An 8g serving of a cocoa blend has well under 20mg of caffeine, against about 75mg in a cup of tea. If you're sensitive, have it earlier.

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