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CBD vs THC: Key Differences, UK Law, Drug Tests and Driving

CBD and THC are both cannabinoids from the cannabis plant, but THC makes you high and CBD doesn’t.

CBD vs THC:  6 Differences You Should Know!

Last updated: October 2026

CBD and THC are both cannabinoids from the cannabis plant, but THC makes you high and CBD doesn’t. In the UK, THC is a controlled Class B drug, while CBD is legal in food supplements that meet the rules. THC also impairs driving and shows up on drug tests.

Below: a side-by-side comparison, effects, legal status, drug tests, driving, medicines that use them, and how to avoid THC.

CBD vs THC at a glance

CBD (cannabidiol) THC (tetrahydrocannabinol)
Gets you high? No Yes
UK legal status Legal in compliant food supplements Controlled, Class B
Addictive? No evidence of abuse potential Can cause dependence
Driving Didn’t impair driving in a 2020 trial; avoid if drowsy Impairs driving; illegal above a very low blood limit
Drug tests Not usually tested for The main thing tests look for
Main source Hemp Drug-type cannabis

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How they affect you

THC strongly activates CB1 receptors in the brain, which causes the high, changes in perception, appetite and memory, and sometimes anxiety or paranoia. FRANK warns that regular cannabis use can lead to dependence and, in some people, mental health problems. CBD binds only weakly to CB1 and acts on several other targets, so it doesn’t change your state of mind. In trials, even large doses of CBD felt like a placebo. See does CBD get you high?, what CBD feels like and the endocannabinoid system.

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Drug tests and driving

  • Drug tests look for THC and its breakdown products, not CBD. A CBD product containing traces of THC could still cause a positive result. See CBD and drug tests.
  • Driving: it’s illegal to drive with certain levels of illegal drugs, including cannabis, in your blood, even if your driving seems fine. Police can use roadside kits that screen for cannabis. A 2020 on-road trial found CBD-dominant cannabis didn’t impair driving, while THC did. Don’t drive if any product makes you drowsy. See CBD and driving.

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Medicines that use CBD and THC

Medicine Contains Licensed in the UK for
Epidyolex Purified CBD Seizures in some rare forms of epilepsy
Sativex THC and CBD spray Muscle spasticity in multiple sclerosis
Nabilone A synthetic THC-like drug Nausea from chemotherapy

These are prescription medicines at much higher doses than supplements. See medical cannabis UK and prescription CBD.

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How to avoid THC

Our CBD oils and capsules are broad spectrum and on the FSA public list. The FSA’s 10mg a day figure is precautionary advice rather than a legal limit, set while longer-term safety research continues. At Evopure we think it is a very cautious figure, and many adults use more. If you go above it, increase slowly, and check with your GP or pharmacist first if you take any medication. We don’t recommend our products during pregnancy or breastfeeding.

For the full picture, see what is CBD? The complete UK guide.

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FAQs

What is the difference between CBD and THC?

THC is intoxicating and a controlled drug in the UK. CBD isn’t intoxicating and is legal in compliant food supplements.

Does CBD contain THC?

Full spectrum products contain some THC. Broad spectrum and isolate have THC removed to non-detectable levels. UK products may contain only tiny traces.

Will CBD show up on a drug test?

Tests look for THC, not CBD, but a product with traces of THC could cause a positive result.

Can I drive after taking CBD?

CBD on its own didn’t impair driving in a 2020 trial, but don’t drive if you feel drowsy, and avoid products containing THC.

Is THC legal in the UK?

No. THC is a Class B drug. It’s only available in specific prescription medicines.

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Sources

Written by

Haseeb Bani

Co-founder and formulation chemist, Evopure

Haseeb is a chemist who spent years formulating supplements before co-founding Evopure. Our articles are general information, not medical advice.

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