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Can CBD Cause Heart Palpitations? What Studies Show and What to Do

CBD can occasionally cause palpitations, but it is uncommon at everyday supplement doses. In trials, a large 600mg dose lowered blood pressure slightly and raised heart rate by up to 10 beats a minute.

a human body with a heart in the middle of it

Last updated: October 2026

CBD can occasionally cause palpitations, but it is uncommon at everyday supplement doses. In trials, a large 600mg dose lowered blood pressure slightly and raised heart rate by up to 10 beats a minute. Palpitations after CBD are more often down to THC in a mislabelled product, caffeine, anxiety or a big first dose.

If palpitations come with chest pain, breathlessness or fainting, call 999. Below: what the research shows about CBD and the heart, the likely causes and what to do about each one, CBD and heart medicines, and when to see a GP.

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Does CBD affect heart rate and blood pressure?

A little, at high doses. The human research is small, mostly in healthy young men, and uses doses far above what most people take. Here is what it shows.

If you’re weighing up CBD for everyday calm, our best CBD oil for anxiety UK guide explains what to check and what the research does and doesn’t show.

Study Who and what dose What it found
Review of 25 studies, 2017 Mostly animal studies across 6 species, plus a few small human ones At rest, CBD had no clear effect on blood pressure or heart rate. Under stress, it reduced the rise in both
Single dose trial, 2017 9 healthy men, 600mg CBD once Resting systolic blood pressure fell by about 6mmHg. Heart rate went up, by about 10 beats a minute during an exercise stress test and 7 during a cold stress test
Seven day trial, 2020 26 healthy men, 600mg CBD a day Resting blood pressure dipped after the first dose, but the effect had gone by day 7. Blood pressure during stress stayed a little lower
Review of trials, 2026 4 randomised trials, 120 adults, 225 to 600mg a day All four saw lower systolic blood pressure than placebo, mainly under stress or during sleep, with bigger effects at higher doses. Side effects were mild to moderate (nausea, diarrhoea, tiredness) and no serious heart events were reported
THC, for comparison Cannabis containing THC The UK drugs advice service FRANK warns that cannabis can increase heart rate and affect blood pressure

The rise in heart rate seen with 600mg is thought to be the body compensating for the small drop in blood pressure. That dose is 60 times the FSA’s 10mg a day figure, so any effect at supplement doses is likely to be much smaller. The UK prescribing information for Epidyolex, a licensed CBD medicine taken at far higher doses, does not list palpitations or a fast heart rate among its side effects.

None of this makes CBD a treatment for high blood pressure or any heart condition. It simply means that if you feel your heart racing after CBD, the CBD itself is rarely the whole story.

Why some people notice palpitations after CBD

Palpitations are when your heartbeat suddenly becomes more noticeable: pounding, fluttering, racing or skipping a beat. The NHS says they are common and not usually a sign of anything serious. When they follow CBD, these are the usual suspects.

  • THC in the product. When UK researchers tested 29 widely sold CBD oils, 55% had measurable THC or cannabinol, both controlled drugs, and only 38% were within 10% of the CBD stated on the label. THC can raise heart rate, so a full spectrum or poorly made product is a more likely trigger than CBD itself.
  • A big first dose, especially on an empty stomach, or several products at once (oil plus gummies plus a CBD drink).
  • Caffeine. In a trial, very high doses of CBD (750mg twice a day) roughly doubled how long caffeine stayed in the body, with its half-life going from 5.4 to 10.9 hours. Everyday doses are a fraction of that, but if you pair CBD with strong coffee, it is worth cutting back. See CBD and coffee.
  • Anxiety. Worrying about a new product, or noticing your heartbeat because you are watching for side effects, can set off a racing heart on its own. Palpitations are a common physical symptom of anxiety.
  • A dip in blood pressure. Large doses can lower blood pressure slightly. If you stand up quickly you may feel light-headed, and your heart speeds up to compensate. The NHS calls this postural hypotension.
  • Something else at the same time. The NHS lists alcohol, caffeine, nicotine, poor sleep, stress, hard exercise, some medicines, the menopause and pregnancy as common triggers, as well as medical causes such as anaemia, an overactive thyroid or a heart rhythm problem.

Possible reasons and what to do

Possible reason Clues What to do
THC in the product Full spectrum or unlabelled product, no batch lab report, feeling “high”, dry mouth, red eyes Stop. Check the batch report for THC. Switch to a broad spectrum product with THC not detected
Dose too high Started above 10mg, took several products, or took it on an empty stomach Go back to a low dose with food and increase slowly, if at all
Caffeine Took CBD with coffee, energy drinks or pre-workout Cut caffeine, or keep it to the morning and take CBD later in the day
Anxiety or panic Fear, fast breathing, tingling, it builds and fades within minutes Slow breathing, sit down, ground yourself. See a GP if it keeps happening
Low blood pressure Dizzy or light-headed on standing Sit or lie down, drink water, get up slowly
A medicine interaction You take blood thinners, statins, blood pressure or heart medicines Stop CBD and speak to your pharmacist or GP before taking it again
An unrelated cause Palpitations happen with or without CBD See a GP, who may arrange an ECG

What to do if it happens

  1. Stop and don’t take any more.
  2. Sit or lie down and breathe slowly.
  3. Drink some water and avoid caffeine and alcohol.
  4. Note the product, dose and time, and check its lab report for THC.
  5. If it passes quickly, mention it to a pharmacist or GP before trying CBD again.

When to see a GP or call 999

Call 999 or go to A&E if palpitations don’t go away, or you also have chest pain, shortness of breath, or feel faint or have fainted. The NHS advises not to drive yourself: ask someone to take you or call an ambulance, and bring any medicines you take.

Get an urgent GP appointment or call 111 if the palpitations have stopped but you had chest pain, breathlessness or fainting with them.

See a GP if you feel well but palpitations keep coming back or are happening more often, last longer than a few minutes, or you have a heart condition or a family history of heart problems. A GP may arrange an ECG, a simple test of your heart’s rhythm.

Full spectrum, broad spectrum and THC

Because THC is the more likely culprit for a racing heart, the type of CBD matters.

  • Full spectrum keeps all the hemp compounds, including some THC. THC is a controlled drug in the UK.
  • Broad spectrum keeps other hemp compounds such as terpenes, with the THC removed.
  • Isolate is CBD on its own.

Our full comparison is in full spectrum vs broad spectrum vs isolate, and CBD vs THC explains the difference between the two cannabinoids. Whatever you buy, check the certificate of analysis for your batch shows THC as not detected. Our guide on how to read a CBD lab report shows where to look.

All Evopure CBD products are broad spectrum with 0% THC, and they are on the FSA’s public list, linked to validated novel food applications. You can read what that means in our guide to the FSA’s CBD decision.

CBD and heart or blood pressure medicines

CBD is broken down by enzymes in the liver, and it can change how much of some medicines stays in your blood. Reviews of the research flag these in particular:

  • Warfarin. A 2023 systematic review found seven case reports, and in six of them warfarin’s blood-thinning effect (the INR) went up. The evidence is very low quality and the cannabis doses were usually very high, but warfarin needs close monitoring, so talk to your anticoagulation clinic first.
  • Statins, beta-blockers and other heart medicines. A 2026 review of cannabinoid interactions covers statins, beta-blockers and warfarin among the common heart and metabolic medicines that need care.
  • Blood pressure medicines. Because large doses of CBD lowered blood pressure in trials, taking it alongside blood pressure tablets could add to dizziness.

Some heart medicines carry a “do not take with grapefruit” warning. That is a useful prompt to ask, though it doesn’t by itself mean CBD will interact, and no warning doesn’t mean a medicine is safe to combine. If you take any heart or blood pressure medicine, speak to your pharmacist or GP before trying CBD. Our guide can CBD interact with medication? covers the grapefruit warning and the main groups of drugs, and is CBD bad for your liver? explains what the trials show about liver enzymes and dose.

How much CBD is sensible?

The FSA’s provisional safe intake for CBD is 10mg a day for a healthy 70kg adult. It also advises that people on prescription medication should not take CBD without the advice of a medical professional, and that pregnant and breastfeeding women should avoid it. We don’t recommend our products during pregnancy or breastfeeding, and they are for adults (18+) only.

The FSA’s 10mg a day figure is precautionary advice rather than a legal limit, set while longer-term safety research continues. At Evopure we think it is a very cautious figure, and many adults use more. If you go above it, increase slowly, and check with your GP or pharmacist first if you take any medication.

For drops per 10mg for each strength, see our CBD dosage guide.

How to lower the chance of palpitations

  • Choose THC-free CBD with a batch lab report showing THC not detected.
  • Start low: around 10mg, with food, and give it a few days before changing anything.
  • Take one product at a time, so you know your total daily amount.
  • Separate it from coffee or cut back on caffeine.
  • Go easy on alcohol, which is a common palpitations trigger in its own right.
  • Try the evening, when you’re resting rather than rushing.
  • Capsules give an exact dose. See CBD oil vs capsules.

For the other side effects people sometimes notice, such as a dry mouth, tiredness or an upset stomach, see CBD side effects.

Sources 13

  1. Jadoon KA, Tan GD, O’Sullivan SE. A single dose of cannabidiol reduces blood pressure in healthy volunteers in a randomized crossover study. JCI Insight, 2017. PMID 28614793.
  2. Sultan SR, O’Sullivan SE, England TJ. The effects of acute and sustained cannabidiol dosing for seven days on the haemodynamics in healthy men: a randomised controlled trial. Br J Clin Pharmacol, 2020. PMID 32128848.
  3. Sultan SR, Millar SA, England TJ, O’Sullivan SE. A systematic review and meta-analysis of the haemodynamic effects of cannabidiol. Front Pharmacol, 2017. PMID 28286481.
  4. Roberts A, Fountzopoulos S, Desai T. The effects of oral cannabidiol supplementation on blood pressure in adults: a systematic review of randomised controlled trials. J Cannabis Res, 2026. PMID 42321899.
  5. Liebling JP et al. An analysis of over-the-counter cannabidiol products in the United Kingdom. Cannabis Cannabinoid Res, 2022. PMID 33998849.
  6. Thai C, Tayo B, Critchley D. A phase 1 open-label, fixed-sequence pharmacokinetic drug interaction trial to investigate the effect of cannabidiol on the CYP1A2 probe caffeine in healthy subjects. Clin Pharmacol Drug Dev, 2021. PMID 33951339.
  7. Smythe MA, Wu W, Garwood CL. Anticoagulant drug-drug interactions with cannabinoids: a systematic review. Pharmacotherapy, 2023. PMID 37740600.
  8. Papakyriakopoulou P, Valsami G, Ismailos G. Cannabinoids and drug-drug pharmacokinetic interactions: deciphering the risks. Br J Clin Pharmacol, 2026. PMID 41633759.
  9. NHS. Heart palpitations.
  10. NHS. Low blood pressure (hypotension).
  11. FSA. Provisional CBD acceptable daily intake: lay summary. GOV.UK.
  12. FRANK. Cannabis.
  13. emc. Epidyolex: summary of product characteristics.

Written by

Co-founder, Evopure

Martin co-founded Evopure and writes about sleep, stress and recovery. Our articles are general information, not medical advice.

Questions, answered

Occasionally. Large doses can raise heart rate slightly as blood pressure dips, but palpitations are more often due to THC, caffeine, anxiety or a big first dose.

In studies, 600mg of CBD lowered blood pressure a little and raised heart rate a few beats a minute. Effects at supplement doses are likely smaller.

Some people notice flutters, often with caffeine, anxiety or THC-containing products. Seek help if they come with chest pain, breathlessness or fainting.

Check with your GP or cardiologist first. CBD can lower blood pressure and interact with some heart medicines.

It can, but night-time palpitations are often linked to caffeine, alcohol, stress or poor sleep. If they keep happening, see a GP.

Yes, stop and speak to a pharmacist or GP before trying again. Get urgent help if you have chest pain, breathlessness or fainting.

In small trials, doses of 225 to 600mg a day lowered systolic blood pressure a little, mostly under stress. CBD isn't a treatment for high blood pressure, so don't use it in place of your medicine.

No serious heart events were reported in the blood pressure trials, but the research is small. If your heartbeat feels irregular, stop CBD and see a GP, who may arrange an ECG.

Ask your pharmacist or GP first. CBD can change how the body handles some medicines, including warfarin, and may add to the effect of blood pressure tablets.

It is more likely than broad spectrum or isolate, because full spectrum contains some THC, and THC can raise heart rate. Check the lab report for THC.

CBD isn't a treatment for palpitations or any heart condition. If you get palpitations, follow the NHS advice and see a GP if they keep coming back.

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