Last updated: 10 November 2026
High cholesterol doesn’t usually make you tired. The NHS says high cholesterol does not usually cause symptoms, and you can only find out you have it from a blood test. If you’re tired and have high cholesterol, the cause is more often something that travels with it, such as statins, an underactive thyroid, type 2 diabetes or sleep apnoea.
iIf you’ve felt tired for a few weeks and aren’t sure why, see a GP. Checked against the NHS high cholesterol, cholesterol levels, NHS Health Check and tiredness pages, the British Thyroid Foundation and the British Heart Foundation in November 2026.
Can high cholesterol make you tired?
High cholesterol on its own is not a known cause of tiredness. Cholesterol is a fatty substance in your blood, and too much of it can block your blood vessels over time, raising the risk of heart attack and stroke. The NHS says it does not usually cause symptoms, which is why so many people only find out from a routine blood test.
So if you feel drained, it’s worth looking for the real cause rather than putting it down to your cholesterol number. These are the healthy levels the NHS gives for adults:
| Cholesterol type (NHS) | Healthy level for adults |
|---|---|
| Total cholesterol | Below 5mmol/L |
| Non-HDL (“bad”) cholesterol | Below 4mmol/L |
| HDL (“good”) cholesterol | Above 1.0mmol/L for men or above 1.2mmol/L for women |
iThe NHS says your own target depends on your age, other health conditions and your risk of heart disease, so ask your GP what your numbers mean for you. For how stress fits in, see does stress cause high cholesterol?
What else causes tiredness when you have high cholesterol?
iSeveral common causes of tiredness either raise cholesterol or tend to turn up alongside it. A GP can check most of them with a blood test or a few questions.
| Possible cause | Link with cholesterol | Does it cause tiredness? |
|---|---|---|
| Statins | The main medicine for high cholesterol | Yes: the NHS lists “feeling more tired or weaker than usual” as a common side effect |
| Underactive thyroid | The British Thyroid Foundation lists raised cholesterol as a feature | Yes: the NHS lists “feeling extremely tired (fatigue)” |
| Type 2 diabetes | A GP may suggest a cholesterol test if you have diabetes | Yes: “feeling very tired” is a common symptom |
| Sleep apnoea | Linked with being overweight, like high cholesterol | Yes: the NHS says you may “feel very tired” in the day |
| Being overweight | The NHS lists it as a cause of high cholesterol | Yes: the NHS lists “feeling very tired (fatigue)” with obesity |
| Alcohol | The NHS lists drinking alcohol as a cause | It breaks up sleep, so you wake less rested |
Statins
If you started a statin and then felt tired, the medicine may be part of it: the NHS lists feeling more tired or weaker than usual, muscle pain and sleep problems among the common side effects. Never stop a statin on your own: your GP can change the dose or try a different one. See do statins make you tired? and, for the CoQ10 question, CoQ10.
Underactive thyroid
An underactive thyroid (hypothyroidism) slows the body down. The NHS lists tiredness, feeling cold, weight gain, constipation and low mood among its symptoms, and the British Thyroid Foundation lists raised cholesterol too. A simple blood test checks it. See underactive thyroid symptoms.
Type 2 diabetes
The NHS lists feeling very tired, peeing more than usual, feeling thirsty all the time and losing weight without trying as common symptoms, but says not everyone with type 2 diabetes has symptoms. See does diabetes make you tired?
Sleep apnoea and weight
Sleep apnoea is when your breathing stops and starts while you sleep. It’s linked with obesity and leaves you very tired in the day, and without treatment it can lead to high blood pressure and heart disease. If someone says you snore loudly or stop breathing at night, see sleep apnoea and a GP.
Low iron, low vitamin B12, poor sleep and low mood are other common causes worth ruling out. See iron deficiency symptoms, vitamin B12 deficiency and, for the bigger picture, why am I always tired?
Does familial hypercholesterolaemia cause tiredness?
No. Familial hypercholesterolaemia (FH) is an inherited condition that causes very high cholesterol from birth, but it doesn’t cause tiredness or usually any symptoms. The British Heart Foundation says it affects about 1 in 250 people, around 270,000 people in the UK, and many don’t know they have it.
Rarely, FH causes visible signs: lumps around the knuckles, knees or Achilles tendon, a pale white ring around the coloured part of the eye, or small yellow patches near the eyelids. If you’re diagnosed, the BHF says your parents, brothers and sisters and children should be checked too, because each has a 1 in 2 chance of having it. If heart disease runs young in your family, ask your GP about a test.
Can tiredness be a sign of heart problems?
Sometimes. Over years, high cholesterol can narrow the arteries and lead to coronary heart disease, whose most common symptoms the NHS gives as chest pain (angina) and breathlessness. Heart failure, which can follow long-term strain from coronary heart disease or high blood pressure, lists feeling weak, light-headed or very tired, particularly after moving, as a symptom.
iTiredness with breathlessness, chest pain or swollen ankles needs a GP appointment, not a wait-and-see. High blood pressure often sits alongside high cholesterol: see normal blood pressure and does high blood pressure make you tired?
How do I find out if I have high cholesterol?
With a blood test. The NHS says ask your GP surgery for a cholesterol test if you’ve not had one before and you’re over 40, overweight, or high cholesterol or heart problems run in your family. Most people don’t need to fast first. Some pharmacies offer tests too, but you may have to pay.
If you’re 40 to 74 and don’t already have heart disease, diabetes or a stroke, the free NHS Health Check includes a cholesterol test and a blood pressure test, and you should be invited every 5 years. If you’re tired as well, mention it: the GP may add other blood tests, such as thyroid, blood sugar and iron.
What to do if you’re tired with high cholesterol
- Don’t blame the number. Ask your GP to look for a cause of the tiredness, especially if it has lasted a few weeks.
- Keep taking your medicine. If you think a statin is making you tired, speak to your GP or pharmacist rather than stopping it.
- Move more. The NHS suggests at least 150 minutes of moderate exercise a week to help lower cholesterol, and regular activity tends to help energy too.
- Eat for your heart. The NHS advises less saturated fat (fatty meat, butter, cakes) and more oily fish, wholegrains, nuts, seeds, fruit and vegetables. See high fibre foods and omega 3.
- Cut back on alcohol and stop smoking. The NHS says not to regularly drink more than 14 units a week, and smoking can raise cholesterol. See alcohol and sleep.
- Protect your sleep. If you sleep 8 hours and still wake tired, see tired after 8 hours of sleep.
When to see a GP or get urgent help
| If you have | What to do |
|---|---|
| Tiredness for a few weeks with no clear reason, or tiredness that affects daily life | See a GP |
| Tiredness with weight loss, mood changes, or loud snoring and gasping in your sleep | See a GP |
| Tiredness you think is from a statin or another medicine | Speak to your GP or pharmacist; don’t stop it on your own |
| Breathlessness lying down or during everyday activity, or sudden weight gain | Urgent GP appointment or NHS 111 |
| Chest pain that feels tight or squeezing, or spreads to your arms, neck or jaw, or severe difficulty breathing | Call 999 |
Supplements with high cholesterol: check first
No supplement fixes tiredness caused by an illness or a medicine, and none replaces cholesterol treatment. If you take a statin or other regular medicines, tell your GP or pharmacist about any supplements or herbal remedies before you start them. Evopure doesn’t sell cholesterol medicines or cholesterol supplements.
CBD: we don’t suggest CBD for anyone taking regular medicines without advice. The FSA advises people taking any medication not to take CBD unless under medical direction. See can CBD interact with medication?
Our pick
Magnesium Glycinate Sleep Complex
Magnesium Glycinate Sleep Complex is a berry drink powder with 290mg of magnesium (77% NRV) per 4.75g serving, from bisglycinate and citrate, plus glycine and L-theanine. Magnesium contributes to a reduction of tiredness and fatigue. It doesn’t treat high cholesterol or a medicine side effect. Check with your GP or pharmacist first.
Add Magnesium Glycinate Sleep Complex to bag See ingredients and reviews
Subscribe and save 25% on your first order, then 20%. New to Evopure? Join our emails for 20% off a one-off first order. Free UK delivery over £45. Vegan and made in the UK.
Subscribe £22.49One-off £29.99
View productOur Reishi Mushroom Adaptogenic Complex isn’t suggested here: its pack says it isn’t for people on medication. For how much magnesium adults need, see how much magnesium per day.
iIf you take any regular medicines, check with your GP or pharmacist first. We don’t recommend our products during pregnancy or breastfeeding. For adults (18+) only.
Next step
Magnesium Glycinate Sleep Complex
If your GP or pharmacist is happy, add the Magnesium Glycinate Sleep Complex to your evening routine: 290mg of magnesium (77% NRV) per 4.75g berry drink. Magnesium contributes to a reduction of tiredness and fatigue.
Add Magnesium Glycinate Sleep Complex to bag See ingredients and reviews
Subscribe and save 25% on your first order, then 20%. New to Evopure? Join our emails for 20% off a one-off first order. Free UK delivery over £45. If you take any regular medicines, check with your GP or pharmacist first. We don’t recommend our products during pregnancy or breastfeeding.
Subscribe £22.49One-off £29.99
View productSources 9
- NHS. High cholesterol (reviewed 13 March 2026), Cholesterol levels, Getting tested and How to lower your cholesterol.
- NHS. NHS Health Check.
- NHS. Statins.
- NHS. Underactive thyroid, and British Thyroid Foundation. Hypothyroidism.
- NHS. Type 2 diabetes symptoms, Sleep apnoea and Obesity.
- British Heart Foundation. Familial hypercholesterolaemia.
- NHS. Coronary heart disease symptoms, Heart failure and Heart attack.
- NHS. Tiredness and fatigue.
- FSA (gov.uk). Cannabidiol (CBD) guidance.
This guide is general information, not medical advice. Always follow your GP and the leaflet that comes with your medicine. Evopure makes the Magnesium Glycinate Sleep Complex and doesn’t make or sell cholesterol medicines.








































