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What Is CBC Oil? Cannabichromene Explained (UK)

CBC oil is an oil containing cannabichromene (CBC), a non-intoxicating cannabinoid that hemp makes from the same parent compound, CBGA, as CBD and THC. CBC is usually a small fraction of hemp extract.

What is CBC Oil? A Guide to Cannabichromene

Last updated: October 2026

CBC oil is an oil containing cannabichromene (CBC), a non-intoxicating cannabinoid that hemp makes from the same parent compound, CBGA, as CBD and THC. CBC is usually a small fraction of hemp extract. Lab and animal studies are interesting, but there are no meaningful human trials of its effects, so any claimed benefits are unproven.

Below: what CBC is, what the research on CBC oil benefits really shows (claim by claim), how CBC compares with CBD, CBG, CBN and THC, UK law and novel food rules, safety and drug tests, and how to spot hype. One quick note: if you searched for “CBC oil” and meant the coconut oil brand, this guide is about the hemp cannabinoid.

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What is CBC oil?

Hemp plants make CBGA, the “parent” cannabinoid, which plant enzymes turn into the acid forms of THC, CBD or CBC. One of those enzymes, CBC synthase, converts CBGA into CBCA, and when CBCA is heated or ages it loses part of its structure and becomes CBC. In many cannabis and hemp varieties CBC is the fourth most abundant cannabinoid after THC, CBD and CBG, but that still means small amounts. See what is CBGA? and our guide to cannabinoids.

CBC doesn’t produce a high. In cell studies it activated the CB2 receptor (found mainly on immune cells) but not CB1, the receptor THC acts on to cause intoxication. It also acts on TRP channels, a family of sensors involved in temperature and pain signalling. If the body’s cannabinoid receptors are new to you, see the endocannabinoid system explained.

“CBC oil” can mean two quite different things:

  • A CBC-dominant oil, made from a CBC isolate or distillate dissolved in a carrier oil. These are rare in the UK.
  • A broad or full spectrum CBD oil that contains some CBC alongside the CBD. This is where most people actually come across CBC. See what is full spectrum CBD?

CBC oil benefits: what the research shows

Most articles on CBC oil benefits list inflammation, pain, acne, mood and brain health. Here is what sits behind each claim. A 2026 review of CBC described it as “profoundly underexplored” and pointed to the absence of clinical trials, and a 2024 review noted that CBC products are already sold over the counter with little or no evidence of their safety or efficacy.

Claimed benefit What has actually been studied Evidence in people
Inflammation Lower inflammation markers in mouse immune cells, and less gut inflammation in a mouse colitis model (2013) None
Pain Fewer pain behaviours in mice given CBC by injection, at up to 20mg per kg of body weight (2023) None
Skin and acne Lower oil (sebum) production in human skin cells grown in a dish (2016) None
Mood Less “depression-like” behaviour in stressed mice, plus computer modelling (2025) None
Seizures Raised the seizure threshold in a mouse model of Dravet syndrome (2021) None
Brain cells Helped mouse neural stem cells survive in a dish (2013) None
Bacteria Antibacterial activity in lab tests (reviewed 2024) None

These are areas researchers are exploring, not proven effects. Results in cells and mice often don’t carry over to people, the mouse doses were injected rather than swallowed, and the 2026 review highlights CBC’s low oral bioavailability, meaning little of a swallowed dose may reach the bloodstream. Claims online that CBC treats depression, acne or pain go well beyond the evidence.

CBC is also mentioned as part of the “entourage effect”, the idea that hemp compounds work better together than alone. It is plausible but unproven: see the entourage effect and what are terpenes?

Has CBC been tested in people?

Barely. The only human study we could find measured how CBC is absorbed, not whether it does anything. In a small pilot study published in 2022, 43 adults took a medical cannabis oil containing CBD, a little THC and about 1.1mg of CBC per ml, for a week. CBC appeared in the blood more readily than expected for its dose compared with CBD and THC. The study was run by a cannabis company, and it didn’t test any health outcome.

So there is no reliable human evidence on what CBC oil does, how much to take, or how it compares with CBD for anything. CBD, by contrast, has been through many human trials. See CBD benefits and side effects.

CBC vs CBD, CBG, CBN and THC

CBC CBD CBG CBN THC
Gets you high? No No No Very mildly at high doses Yes
Amount in hemp Small Main cannabinoid in hemp Small Trace (forms as THC ages) Very low in hemp
Human research Almost none The most studied, including licensed medicine trials Very limited A handful of small trials Extensive
UK status Not named as controlled; novel food rules apply Legal in compliant food supplements Not named as controlled; novel food rules apply Controlled (Class B) Controlled (Class B)
Our guide This page Hemp oil vs CBD oil CBG vs CBD CBD vs CBN CBD vs THC

The short version: CBC and CBG are both non-intoxicating minor cannabinoids with mostly lab research behind them, CBN and THC are controlled drugs in the UK, and CBD is the only one with a substantial body of human research. For more of the alphabet, see what is THCV? and what is CBDV?

Is there CBC in Evopure’s oils?

We don’t sell a CBC oil, and we don’t make any claims for CBC. Our CBD oils are broad spectrum. As our product pages explain, broad spectrum keeps the wider range of hemp cannabinoids and terpenes, including minor cannabinoids such as CBC, with the THC taken out (0% THC). The amounts of minor cannabinoids are small and vary from batch to batch, so the batch lab report (certificate of analysis, or COA) is the place to check.

Our Broad Spectrum CBD Oil contains just broad spectrum CBD and organic MCT oil, with roughly 2.5mg, 5mg or 10mg of CBD per drop depending on strength. Our CBD products are on the FSA public list, linked to validated novel food applications RP438, RP821 and RP47. They are for adults (18+) only, and we don’t recommend our products during pregnancy or breastfeeding.

The FSA’s 10mg a day figure is precautionary advice rather than a legal limit, set while longer-term safety research continues. At Evopure we think it is a very cautious figure, and many adults use more. If you go above it, increase slowly, and check with your GP or pharmacist first if you take any medication.

Is CBC safe? Side effects and drug tests

Honestly, nobody knows much yet. There is very little human safety data on CBC on its own, and no long-term studies. What the lab work does show is worth knowing:

  • Liver. In a 2025 lab model of human liver tissue, CBC showed signs of moderate liver cell stress at the doses tested, more than CBD, CBN or CBG did. That is a lab model, not people, but it is a reason not to treat concentrated CBC as harmless.
  • Medicines. CBC is broken down by the same liver enzyme system (cytochrome P450) that handles many medicines, so interactions are possible. If you take any medication, ask your GP or pharmacist first. See will CBD interact with medication?
  • Pregnancy and young people. There is no safety data. Avoid cannabinoid products if you are pregnant or breastfeeding, and they are for adults only. See CBD oil in pregnancy.

Drug tests. Standard workplace drug tests look for a breakdown product of THC, not for CBC or CBD. In a US study, pure CBD didn’t produce a positive urine test, while a CBD product that also contained THC did. So with any hemp product, the risk comes from trace THC, which is why a batch report showing THC not detected matters. Athletes are different: UK Anti-Doping says all cannabinoids other than CBD are prohibited in competition, with no reporting threshold for trace amounts, and CBC is one of them. See does CBD show up on a drug test? and CBD side effects.

How much CBC should you take?

There is no evidence-based CBC dose, because there are no human trials of its effects. Treat any “recommended CBC dose” on a label as a guess. In a broad spectrum oil, the CBC per drop is a tiny fraction of the CBD, so the dose that matters is the CBD dose. See how much CBD should I take? and how to take CBD oil.

How to spot CBC hype

In the UK, you can’t claim or imply that a food or supplement treats, prevents or cures any disease or medical condition. So a CBC product sold as a treatment for depression, acne, pain or anything else is breaking the rules, whatever the research looks like. Before you buy any CBC oil, check for:

  • A batch lab report from an accredited lab showing how much CBC is actually in the bottle, and that THC isn’t detected.
  • A link to the FSA public list, or a named novel food application the product sits under.
  • No medical claims and no “miracle” or “super cannabinoid” language.
  • A clear amount of CBC per serving that matches the lab report, rather than a vague “rich in CBC”.
  • Realistic expectations: if the evidence is mostly mice, the honest marketing should say so.

If you want a well-studied cannabinoid product that is legal to sell in the UK, a broad spectrum CBD oil with a batch lab report is the established choice. See the best CBD oils in the UK.

Sources 19

  1. Elbouzidi A et al (2026). Cannabichromene (CBC): a comprehensive review of biosynthesis, pharmacology, therapeutic potential, and translational perspectives. Journal of Cannabis Research.
  2. Sepulveda DE et al (2024). The potential of cannabichromene (CBC) as a therapeutic agent. Journal of Pharmacology and Experimental Therapeutics.
  3. Peters EN et al (2022). Pharmacokinetics of cannabichromene in a medical cannabis product also containing cannabidiol and Δ9-tetrahydrocannabinol: a pilot study. European Journal of Clinical Pharmacology.
  4. Udoh M et al (2019). Cannabichromene is a cannabinoid CB2 receptor agonist. British Journal of Pharmacology.
  5. Romano B et al (2013). The cannabinoid TRPA1 agonist cannabichromene inhibits nitric oxide production in macrophages and ameliorates murine colitis. British Journal of Pharmacology.
  6. Raup-Konsavage WM et al (2023). Antinociceptive effects of cannabichromene (CBC) in mice. Biomedicines.
  7. Oláh A et al (2016). Differential effectiveness of selected non-psychotropic phytocannabinoids on human sebocyte functions. Experimental Dermatology.
  8. Sharma A et al (2025). Cannabichromene in major depressive disorder: in silico and in vivo explorations. Naunyn-Schmiedeberg’s Archives of Pharmacology.
  9. Anderson LL et al (2021). Cannabichromene, related phytocannabinoids, and 5-fluoro-cannabichromene have anticonvulsant properties in a mouse model of Dravet syndrome. ACS Chemical Neuroscience.
  10. Shinjyo N, Di Marzo V (2013). The effect of cannabichromene on adult neural stem/progenitor cells. Neurochemistry International.
  11. Larson JD et al (2025). Hepatotoxicity evaluation of cannabidiol, cannabinol, cannabichromene and cannabigerol using a human quad culture liver chip. Scientific Reports.
  12. Roy P et al (2024). Elucidating the mechanism of metabolism of cannabichromene by human cytochrome P450s. Journal of Natural Products.
  13. Spindle TR et al (2020). Urinary pharmacokinetic profile of cannabinoids following administration of vaporized and oral cannabidiol and vaporized CBD-dominant cannabis. Journal of Analytical Toxicology.
  14. Home Office. Drug licensing factsheet: cannabis, CBD and other cannabinoids.
  15. Food Standards Agency. Cannabidiol (CBD) guidance.
  16. Food Standards Agency. Novel foods authorisation guidance.
  17. Food Standards Agency. CBD products linked to novel food applications (public list).
  18. GOV.UK. Nutrition, health claims and supplement labelling.
  19. UK Anti-Doping. Cannabidiol (CBD).

This guide is general information, not medical or legal advice.

Written by

Co-founder, Evopure

Martin co-founded Evopure and writes about sleep, stress and recovery. Our articles are general information, not medical advice.

Questions, answered

An oil containing cannabichromene, a non-intoxicating cannabinoid from hemp. It's rare in the UK and has very little human research.

No. CBC isn't intoxicating and doesn't act on the brain like THC.

There's no evidence it is. CBD is far more studied; CBC research is mostly in cells and animals.

It isn't named as a controlled drug, but products need novel food authorisation and must not contain THC.

Lab and animal studies have looked at inflammation, pain and skin, but nothing has been shown in people yet.

None are proven. Researchers are exploring inflammation, pain, skin, mood and seizures in cells and mice, but there are no human trials of CBC's effects.

Standard workplace tests look for THC, not CBC. The risk with any hemp product is trace THC, so check the lab report. Athletes should note that UK Anti-Doping prohibits all cannabinoids other than CBD in competition.

Usually a little. Broad spectrum oils keep minor cannabinoids such as CBC with the THC removed. The amount is small and varies by batch, so check the lab report.

Most people who take CBC already do, because it comes as part of broad or full spectrum CBD oil. If you take any medication, check with your GP or pharmacist first.

There is very little human safety data. A lab model of liver tissue showed some liver cell stress with CBC, and it may interact with medicines. It is not suitable in pregnancy, while breastfeeding or for under-18s.

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