Ashwagandha is one of the most widely used adaptogenic herbs for stress, sleep and resilience. But like any active supplement, it can cause side effects in some people.
For many, ashwagandha is well tolerated. For others, it may trigger unwanted reactions — especially if taken at high doses, combined with certain medications, or used despite underlying health conditions.
This guide breaks down common and rare ashwagandha side effects, who should avoid it, and how to reduce risk.
Common ashwagandha side effects
The most frequently reported side effects tend to be mild and dose-related:
- Digestive upset (nausea, stomach discomfort, diarrhoea)
- Drowsiness or fatigue, especially when combined with other calming supplements
- Headache
- Feeling “too relaxed” or flat at higher doses
These effects often improve by lowering the dose or taking ashwagandha with food.
Less common & rare side effects
Less commonly, some people report:
1. Hormonal effects
Ashwagandha can influence cortisol and thyroid hormones. In people with thyroid conditions (especially hyperthyroidism), this may worsen symptoms.
2. Changes in mood
While many people feel calmer, a small number report irritability, emotional blunting or restlessness.
3. Liver-related concerns (rare)
Rare cases of liver injury linked to ashwagandha supplements have been reported, often involving high doses, long-term use, or contaminated products.
This is uncommon, but it’s one reason quality and dosing matter.
Who should avoid ashwagandha?
Ashwagandha is not suitable for everyone. You should avoid or seek medical advice before using it if you:
- Are pregnant or breastfeeding
- Have a thyroid disorder
- Have autoimmune conditions
- Have a history of liver disease
- Take medications that affect hormones, sedation or immune function
Read more: Ashwagandha & Breastfeeding: Is It Safe?
Medication & supplement interactions
Ashwagandha may interact with:
- Sedatives or sleep medications
- Anti-anxiety or antidepressant medications
- Thyroid medication
- Immunosuppressants
If you take prescription medication, speak with a GP or pharmacist before adding ashwagandha.
How to use ashwagandha more safely
1. Start low
Many side effects happen at higher doses. Start with the lowest effective amount.
2. Use it consistently, not aggressively
Ashwagandha works best over time. More is not better.
3. Avoid stacking multiple sedating supplements
Combining ashwagandha with alcohol, strong sleep aids or sedatives increases side effect risk.
4. Take breaks
Some people benefit from cycling adaptogens rather than using them continuously.
Ashwagandha in Evopure products
Evopure uses ashwagandha in carefully balanced formulations designed for daily stress resilience, not aggressive dosing.
- Flow CBD Oil – broad-spectrum CBD + ashwagandha for calm focus
- Sleep CBD Oil – for evening wind-down (no ashwagandha)
- Magnesium Sleep Blend – a non-adaptogen alternative for sleep & nervous system support
Note: If ashwagandha doesn’t suit you, magnesium and CBD-only formulas may be gentler options.
Frequently asked questions
Is ashwagandha safe for daily use?
For many adults, yes — at appropriate doses. However, daily use isn’t ideal for everyone, especially those with thyroid or autoimmune conditions.
Can ashwagandha cause anxiety?
Rarely, some people feel more restless or emotionally flat. Lowering the dose or stopping usually resolves this.
Does ashwagandha affect hormones?
Yes. It can influence cortisol and thyroid hormones, which is why caution is advised for certain groups.
Is magnesium a safer alternative?
For many people, yes. Magnesium supports relaxation without hormonal effects and is widely tolerated.
Final thoughts
Ashwagandha can be a powerful tool for stress and sleep — but it isn’t risk-free.
Choosing quality products, using sensible doses, and knowing whether it’s appropriate for your health profile are key to avoiding side effects.
If in doubt, magnesium or CBD-only formulas can offer calmer support with a gentler safety profile.
